Adherent cell production.
Simplified.
High surface area. Compact footprint.
From lab-scale to large-scale, the CellScrew® helps to overcome scaling bottlenecks in your adherent cell expansion process.
Book a call Download brochureSame surface, less vessels.
CellScrew® is a dynamic adherent cell culture flask that preserves cell biology while dramatically reducing vessel count and footprint.
One CellScrew® 10K replaces 57 T-175 flasks or 12 roller bottles, consolidating capacity into a single format and avoiding system changes while scaling. The compact, lightweight design simplifies routine workflows and leverages operational footprint.
Less vessels = less work, lower risk, optimized space use
Manual labor drives up to 71% of therapeutic production costs¹. CellScrew® cuts 92% of incubator footprint vs. roller bottles, maximizing cultivation surface area. With a 33% reduction in handling time and less vessels to handle, CellScrew® ensures efficient, high-quality cultivation to prevent batch loss.
Explore our data and application notes to learn about the features in detail.
Scale with confidence: reproducible results across all stages.
The transfer from lab to commercial scale is a time- and resource-intensive process. We help to speed up the scaling process by providing a solution for every step towards accessible therapy.
Available size variants ranging from 850 cm² to 10,000 cm² with comparable process engineering characteristics make it easy for you to scale your cell cultivation process up or down without the need for complex process development.
Your benefits with the CellScrew®
Cuts hands-on time and vessels
Cuts hands-on time and vessels
Faster work, lower contamination, and more incubator space available.
Scales without changing formats
Scales without changing formats
All CellScrew® sizes share surface and process logic: Develop once, scale unchanged.
Robust, reproducible results
Robust, reproducible results
Defined mixing and oxygen coefficient give reproducible, operator-independent results akin to benchtop bioreactors.
Lower carbon footprint & waste stacks
Lower carbon footprint & waste stacks
PLA and low material-to-surface ratio cut emissions resulting in 90% lower carbon footprint compared to polystyrene stacks.
Short, reliable supply chain
Short, reliable supply chain
Made in Germany with only two raw inputs and a ISO 9001:2015 certified quality management system.
Your first step to simpler adherent cell culture
Save 30% on your CellScrew® Evaluation Pack —
9x CellScrew® mini, TriDock adapter, and optional roller device loaner included. The simplest way to experience fewer flasks, less media, and less handling.
Using CellScrew® in GMP environment
Avoiding the cliff-edge of having to change format mid-journey, the CellScrew® can take you from research through clinical and commercial manufacturing. With the CellScrew® CCT, we’re introducing a configurable closed transfer version for aseptic fluid transfer workflows.
Applications for the CellScrew®
Scalable expansion of adherent cell lines like MSCs, and iPS cells for Cell and Gene Therapy applications.
Scalable production of functional macrophages for the Monocyte Activation Test (MAT) and emerging macrophage-based therapies.
Supports virus-producing adherent cell lines such as Vero and HEK293 for vaccine development, viral vector production and large-scale manufacturing.
The genius in the bottle
The innovative internal structure of the CellScrew® forms a large growth surface on a small footprint and fosters optimal growth conditions with low shear forces and excellent gas exchange.
Constant and homogeneous supply with oxygen and nutrients facilitate robust cell growth while scaling. Manufactured from plant-based material PLA (polylactic acid), this product also comes with a significant reduction in material use and carbon emissions, making the cultivation of cells more sustainable.
Learn about sustainabilityQuality by design
Every CellScrew® undergoes rigorous testing to ensure consistency, reliability, and top-quality performance. Quality criteria like ready to use, biocompatibility and full traceability ensure each unit meets strict industry requirements and is suitable to be used in your regulatory setting.
Visit quality pageThe CellScrew® combines the advantages of other systems for your adherent cell cultivation
Find out how the CellScrew® compares to your current cell cultivation system
- growth surface for adherent cells
- excellent mixing and gas exchange
- one cultivation vessel with maximized surface
- small footprint efficiently used
- easy handling
- streamlined process
- good distribution of media and gases
- compatibility with roller devices
- growth surface for adherent cells
- one cultivation vessel with maximized surface
- small footprint efficiently used
- easy handling
- streamlined process
- large growth surface area for adherent cells
- excellent mixing and gas exchange
- small footprint efficiently used
- easy handling
- streamlined process
- large growth surface area for adherent cells
- excellent mixing and gas exchange
- small footprint efficiently used
- easy handling
- homogeneous, low shear-force cultivation conditions
- no extensive purification processes needed
- streamlined process
Contact us to learn more, visit our FAQ for the most common questions, or book a demo call to speak to our team to clear any questions.
Book yourself a spot to learn about how the CellScrew® can help you to simplify your cell expansion process.
