CellScrew® CCT
Up to 10,000 cm² growth surface. Fully closed liquid handling. Customized to your process.
Download brochure Request customizationFrom flexible research to locked-in GMP processes
Early-stage workflows allow change. GMP manufacturing does not. Decisions made during process development can become costly constraints later — especially when open handling and fragmented liquid transfer are built into the system. The CellScrew® CCT integrates closed processing from the start, supporting scalable and contamination-safe expansion.
Built around your process
The CellScrew® CCT is available in 6,000 cm² and 10,000 cm² formats, based on the proven, TC-treated and gamma-sterilized CellScrew® technology.
The customizable cap assembly allows selection of tubing type, connectors, dip tubes, and venting configurations — enabling seamless integration into existing closed processing workflows and GMP-aligned manufacturing environments.
Your benefits with the CellScrew® CCT
Eliminates open handling risk
Eliminates open handling
risk
No open vessels, no laminar flow cabinet dependency, no operator-to-operator variability.
Configurable to your workflow
Configurable to your
workflow
Select tubing type, connector format, dip tube length, and venting configuration.
GMP-ready from day one
GMP-ready from day one
Your process parameters will transfer directly to GMP without redesigning liquid handling around a new format.
Contamination risk maanged by design
Contamination risk managed by design
Closed architecture removes the primary contamination vector in adherent cell culture.
Scales from 6K to 10K without format change
Scales from 6K to 10K without format change
Scale-up from 6,000 cm² to 10,000 cm² carries your closed workflow forward unchanged.
Same surface, less vessels.
CellScrew® is a dynamic adherent cell culture flask that preserves cell biology while dramatically reducing vessel count and footprint.
One CellScrew® 10K replaces 57 T-175 flasks or 12 roller bottles, consolidating capacity into a single format and avoiding system changes while scaling. The compact, lightweight design simplifies routine workflows and leverages operational footprint.
Less vessels = less work, lower risk, optimized space use
Manual labor drives up to 71% of therapeutic production costs¹. CellScrew® cuts 92% of incubator footprint vs. roller bottles, maximizing cultivation surface area. With a 30% reduction in handling time and less vessels to handle, CellScrew® ensures efficient, high-quality cultivation to prevent batch loss.
Explore our data and application notes to learn about the features in detail.
Applications for the CellScrew® CCT
Supports containment from seeding through harvest without requiring dedicated closed processing equipment beyond the vessel itself.
Removes the manual aseptic steps that introduce the most variability, supporting consistent expansion of HEK293, MSCs, and iPSCs in a format that can be qualified for GMP without process redesign.
Quality by design
Every CellScrew® undergoes rigorous testing to ensure consistency, reliability, and top-quality performance. Quality criteria like ready to use, biocompatibility and full traceability ensure each unit meets strict industry requirements and is suitable to be used in your regulatory setting.
Visit quality pageContact us to learn more, visit our FAQ for the most common questions, or book a demo call to speak to our team to clear any questions.
Book yourself a spot to learn about how the CellScrew® can help you to simplify your cell expansion process.
