HEK-293 Seed Train Expansion with CellScrew®
HEK-293 seed train, transformed.
Simplifying seed-train production
HEK-293 cells are widely used for producing recombinant proteins, monoclonal antibodies, and viral vectors, such as AAV for cell and gene therapies. HEK-293 cells present specific challenges in seed train design — their adherent growth requirements traditionally demand a large number of individual vessels, significant incubator space, and repetitive manual handling at each passage.
CellScrew® addresses this directly by consolidating multiple expansion stages into a single vessel format that scales without format change, and replacing multiple stacks and roller bottles.
HEK seed train workflow using CellScrew®
- High and homogenous HEK cell growth
- 92% reduction in operational footprint (compared to roller bottles)
- 33% reduction in operator handling time (compared to stacks)
CellScrew® advantage: dynamic movement and miniaturization
Free up space in your incubator
These benefits translate directly into fewer vessels to track, fewer media exchange steps per passage, and a smaller biosafety cabinet or laminar flow workload per production cycle — reducing both the time and contamination risk associated with open-vessel handling at scale.
Want to try the CellScrew®?
Great, let’s talk! We can walk you through the operation of the CellScrew®, answer any questions and sort you out with an evaluation package.
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