CellScrew® for Vaccine Manufacturing: Replacing Roller Bottles in Adherent Cell Culture
Adherent cell culture for animal & human vaccine production
Reducing the operational footprint of vaccine production using CellScrew® adherent cell culture vessels
CellScrew ®— a smart alternative to roller bottle workflows
Animal and human viral vaccines rely heavily on adherent cell culture, including Vero, MDCK, and BHK-21 cell lines, often scaled using large numbers of roller bottles. These workflows are operator-intensive and contamination-prone. CellScrew® is a compact, single-use, high-surface-area vessel that runs on standard rollers and replaces ~12 roller bottles per CellScrew® 10K unit, reducing vessel count, footprint, and handling risk.
Reduce your operational footprint
Using a single CellScrew® instead of multiple roller bottles can help you reduce handling steps, laboratory footprint, and operational complexity in your vaccine production workflow.
Download our white paperCellScrew® advantage: dynamic movement and miniaturization
CellScrew® is a 3D printed high surface area cell culture vessel for adherent cell expansion under dynamic conditions. Its internal screw-like architecture maximizes growth surface in a compact format, while controlled rotation promotes uniform media movement and gas exchange. This supports low-shear, efficient, and controllable adherent cell cultivation.
Fewer units, same output.
In vaccine production, the dominant roller bottle paradigm scales by multiplying vessels, driving cost, space, labor, and contamination risk.
CellScrew® directly addresses the most load-bearing constraints of adherent vaccine manufacturing — logistics, footprint, manual handling, and contamination exposure — while offering a pragmatic migration route for validated processes.
CellScrew® directly addresses the most load-bearing constraints of adherent vaccine manufacturing — logistics, footprint, manual handling, and contamination exposure — while offering a pragmatic migration route for validated processes.
Want to try the CellScrew®?
Great, let’s talk! We can walk you through the operation of the CellScrew®, answer any questions and sort you out with an evaluation package.
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